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Enrolling multiple groups in a study (such as those with a condition and healthy controls)?

How to complete your myIRB application if you have multiple groups in a study (such as those with a condition and healthy controls).  Be sure all appropriate sections of your myIRB application (such as inclusion/exclusion criteria and methods sections) and consent include appropriate information about both populations. Remember to discuss use of existing data, tissues, or previous study data if these are being used as control or comparisons in the study.